Yi Zuo
Key Publications
Tonghui Xu, Xinzhu Yu, Andrew J. Perlik, Willie F. Tobin, Jonathan A. Zweig, Kelly A. Tennant, Theresa A. Jones, Yi Zuo (2009) Rapid formation and selective stabilization of synapses for enduring motor memories. Nature
Min Fu, Xinzhu Yu, Ju Lu, Yi Zuo (2012) Repetitive motor learning induces coordinated formation of clustered dendritic spines in vivo. Nature
Chih‐Cheng Chen, Ju Lu, Renzhi Yang, Jun Ding, Yi Zuo (2017) Selective activation of parvalbumin interneurons prevents stress-induced synapse loss and perceptual defects. Molecular Psychiatry
Lindsay P. Cameron, Robert J. Tombari, Ju Lu, Alexander J. Pell, Zefan Q. Hurley, Yann Ehinger, Maxemiliano V. Vargas, Matthew N. McCarroll, Jack C. Taylor, Douglas Myers-Turnbull, Taohui Liu, Bianca Yaghoobi, Lauren J. Laskowski, Emilie I. Anderson, Guoliang Zhang, Jayashri Viswanathan, Brandon M. Brown, Michelle Tjia, Lee E. Dunlap, Zachary Rabow, Oliver Fiehn, Heike Wulff, John D. McCorvy, Pamela J. Lein, David Kokel, Dorit Ron, Jamie Peters, Yi Zuo, David E. Olson (2020) A non-hallucinogenic psychedelic analogue with therapeutic potential. Nature
Ju Lu, Michelle Tjia, Brian Mullen, Bing Cao, Kacper Łukasiewicz, Sajita Shah-Morales, Sydney Weiser, Lindsay P. Cameron, David E. Olson, Lu Chen, Yi Zuo (2021) An analog of psychedelics restores functional neural circuits disrupted by unpredictable stress. Molecular Psychiatry
Feng Lin, Janine M. Simmons, Adam Turnbull, Yi Zuo, Yeates Conwell, Kuan Hong Wang (2025) Cross-Species Framework for Emotional Well-Being and Brain Aging. JAMA Psychiatry
Rochelle L. Coulson, Valentina Frattini, Sarah Morse, Jennifer Hodges, Peter Walter, Philippe Mourrain, Yi Zuo, Gordon Wang (2024) Translational modulator ISRIB alleviates synaptic and behavioral phenotypes in Fragile X syndrome. iScience
Emily Kogan, Ju Lu, Yi Zuo (2023) Cortical circuit dynamics underlying motor skill learning: from rodents to humans. Frontiers in Molecular Neuroscience
Feng Lin, Yi Zuo, Yeates Conwell, Kuan Hong Wang (2023) New horizons in emotional well‐being and brain aging: Potential lessons from cross‐species research. International Journal of Geriatric Psychiatry
Marie Gredell, Ju Lu, Yi Zuo (2023) The effect of single-cell knockout of Fragile X Messenger Ribonucleoprotein on synaptic structural plasticity. Frontiers in Synaptic Neuroscience
Steven F. Grieco, Eero Ċastrén, Gitte M. Knudsen, Alex C. Kwan, David E. Olson, Yi Zuo, Todd C. Holmes, Xiangmin Xu (2022) Psychedelics and Neural Plasticity: Therapeutic Implications. Journal of Neuroscience
Ju Lu, Michelle Tjia, Brian Mullen, Bing Cao, Kacper Łukasiewicz, Sajita Shah-Morales, Sydney Weiser, Lindsay P. Cameron, David E. Olson, Lu Chen, Yi Zuo (2021) An analog of psychedelics restores functional neural circuits disrupted by unpredictable stress. Molecular Psychiatry
Xiaokuang Ma, Jing Wei, Yuehua Cui, Baomei Xia, Le Zhang, Antoine Nehme, Yi Zuo, Deveroux Ferguson, Pat Levitt, Shenfeng Qiu (2021) Disrupted Timing of MET Signaling Derails the Developmental Maturation of Cortical Circuits and Leads to Altered Behavior in Mice. Cerebral Cortex
Katherine M. Bland, Adam Aharon, Eden L. Widener, Mi‐Ryoung Song, Zachary O. Casey, Yi Zuo, George S. Vidal (2021) FMRP regulates the subcellular distribution of cortical dendritic spine density in a non-cell-autonomous manner. Neurobiology of Disease
James Perna, Ju Lu, Brian Mullen, Taohui Liu, Michelle Tjia, Sydney Weiser, James B. Ackman, Yi Zuo (2021) Perinatal Penicillin Exposure Affects Cortical Development and Sensory Processing. Frontiers in Molecular Neuroscience
Kacper Łukasiewicz, Jacob J. Baker, Yi Zuo, Ju Lu (2021) Serotonergic Psychedelics in Neural Plasticity. Frontiers in Molecular Neuroscience
Taohui Liu, Ju Lu, Kacper Łukasiewicz, Bing‐Xing Pan, Yi Zuo (2021) Stress induces microglia-associated synaptic circuit alterations in the dorsomedial prefrontal cortex. Neurobiology of Stress
Shaorong Ma, Yi Zuo (2021) Synaptic modifications in learning and memory – A dendritic spine story. Seminars in Cell and Developmental Biology
Lindsay P. Cameron, Robert J. Tombari, Ju Lu, Alexander J. Pell, Zefan Q. Hurley, Yann Ehinger, Maxemiliano V. Vargas, Matthew N. McCarroll, Jack C. Taylor, Douglas Myers-Turnbull, Taohui Liu, Bianca Yaghoobi, Lauren J. Laskowski, Emilie I. Anderson, Guoliang Zhang, Jayashri Viswanathan, Brandon M. Brown, Michelle Tjia, Lee E. Dunlap, Zachary Rabow, Oliver Fiehn, Heike Wulff, John D. McCorvy, Pamela J. Lein, David Kokel, Dorit Ron, Jamie Peters, Yi Zuo, David E. Olson (2020) A non-hallucinogenic psychedelic analogue with therapeutic potential. Nature
Melod Mehdipour, Taha Mehdipour, Colin M. Skinner, Nathan Wong, Chao Liu, Chia-Chien Chen, Ok Hee Jeon, Yi Zuo, Michael J. Conboy, Irina M. Conboy (2020) Plasma dilution improves cognition and attenuates neuroinflammation in old mice. GeroScience
Ju Lu, Yi Zuo (2020) Shedding light on learning and memory: optical interrogation of the synaptic circuitry. Current Opinion in Neurobiology
Jim McBurney-Lin, Ju Lu, Yi Zuo, Hongdian Yang (2019) Locus coeruleus-norepinephrine modulation of sensory processing and perception: A focused review. Neuroscience & Biobehavioral Reviews
Anish K. Simhal, Yi Zuo, Marc M. Perez, Daniel V. Madison, Guillermo Sapiro, Kristina D. Micheva (2019) Multifaceted Changes in Synaptic Composition and Astrocytic Involvement in a Mouse Model of Fragile X Syndrome. Scientific Reports
Taylor A. Clark, Colin T. Sullender, Daron Jacob, Yi Zuo, Andrew K. Dunn, Theresa A. Jones (2019) Rehabilitative Training Interacts with Ischemia-Instigated Spine Dynamics to Promote a Lasting Population of New Synapses in Peri-Infarct Motor Cortex. Journal of Neuroscience
Melod Mehdipour, Jessy Etienne, Chia‐Chien Chen, Ranveer Gathwala, Maryam Rehman, Cameron Kato, Chao Liu, Yutong Liu, Yi Zuo, Michael J. Conboy, Irina M. Conboy (2019) Rejuvenation of brain, liver and muscle by simultaneous pharmacological modulation of two signaling determinants, that change in opposite directions with age. Aging
Miao Jing, Peng Zhang, Guangfu Wang, Jiesi Feng, Lukas Mesik, Jianzhi Zeng, Huoqing Jiang, Shaohua Wang, Jess C Looby, Nick A. Guagliardo, Linda W. Langma, Ju Lu, Yi Zuo, David A. Talmage, Lorna W. Role, Paula Q. Barrett, Li I. Zhang, Minmin Luo, Yan Song, Jie Zhu, Yulong Li (2018) A genetically encoded fluorescent acetylcholine indicator for in vitro and in vivo studies. Nature Biotechnology
Sarah Morse, Yi Zuo (2018) Cortical dendritic spine development and plasticity: insights from in vivo imaging. Current Opinion in Neurobiology
Esther Park, Michelle Tjia, Yi Zuo, Lu Chen (2018) Postnatal Ablation of Synaptic Retinoic Acid Signaling Impairs Cortical Information Processing and Sensory Discrimination in Mice. Journal of Neuroscience
Taylor A. Clark, Min Fu, Andrew K. Dunn, Yi Zuo, Theresa A. Jones (2018) Preferential stabilization of newly formed dendritic spines in motor cortex during manual skill learning predicts performance gains, but not memory endurance. Neurobiology of Learning and Memory
Sarah Morse, Emma Hiolski, David J. Marcinek, Kathi A. Lefebvre, Donald R. Smith, Yi Zuo (2018) Repeated low level domoic acid exposure increases CA1 VGluT1 levels, but not bouton density, VGluT2 or VGAT levels in the hippocampus of adult mice. Harmful Algae
Xiaodong Tao, Ju Lu, Tuwin Lam, Ramiro Rodriguez, Yi Zuo, Joel Kubby (2017) A three-photon microscope with adaptive optics for deep-tissue in vivo structural and functional brain imaging. Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Michelle Tjia, Xinzhu Yu, Lavpreet S. Jammu, Ju Lu, Yi Zuo (2017) Pyramidal Neurons in Different Cortical Layers Exhibit Distinct Dynamics and Plasticity of Apical Dendritic Spines. Frontiers in Neural Circuits
Chih‐Cheng Chen, Ju Lu, Renzhi Yang, Jun Ding, Yi Zuo (2017) Selective activation of parvalbumin interneurons prevents stress-induced synapse loss and perceptual defects. Molecular Psychiatry
Jennifer Hodges, Xinzhu Yu, Anthony Gilmore, Hannah Bennett, Michelle Tjia, James Perna, Chia-Chien Chen, Xiang Li, Ju Lu, Yi Zuo (2016) Astrocytic Contributions to Synaptic and Learning Abnormalities in a Mouse Model of Fragile X Syndrome. Biological Psychiatry
Ju Lu, Yi Zuo (2016) Clustered structural and functional plasticity of dendritic spines. Brain Research Bulletin
Yang Yang, Danqian Liu, Weitong Huang, Juan Deng, Yan-Gang Sun, Yi Zuo, Mu‐ming Poo (2016) Selective synaptic remodeling of amygdalocortical connections associated with fear memory. Nature Neuroscience
Ju Lu, Yi Zuo (2015) Forgetfulness illuminated. Nature
Ajmal Zemmar, Oliver Weinmann, Yves Kellner, Xinzhu Yu, Raúl Vicente, Miriam Gullo, H. Kasper, Karin Lussi, Z. Ristic, Andreas R. Luft, Mengia-S. Rioult-Pedotti, Yi Zuo, Marta Zagrebelsky, Martin E. Schwab (2014) Neutralization of Nogo-A Enhances Synaptic Plasticity in the Rodent Motor Cortex and Improves Motor Learning in Vivo. Journal of Neuroscience
Chia‐Chien Chen, Ju Lu, Yi Zuo (2014) Spatiotemporal dynamics of dendritic spines in the living brain. Frontiers in Neuroanatomy
Chia‐Chien Chen, Anthony Gilmore, Yi Zuo (2014) Study Motor Skill Learning by Single-pellet Reaching Tasks in Mice. Journal of Visualized Experiments
Xinzhu Yu, Yi Zuo (2014) Two-Photon <em>in vivo</em> Imaging of Dendritic Spines in the Mouse Cortex Using a Thinned-skull Preparation. Journal of Visualized Experiments
Xinzhu Yu, Gordon Wang, Anthony Gilmore, Ada X. Yee, Xiang Li, Tonghui Xu, Stephen J Smith, Lu Chen, Yi Zuo (2013) Accelerated Experience-Dependent Pruning of Cortical Synapses in Ephrin-A2 Knockout Mice. Neuron
Maja Djurišić, George S. Vidal, Miriam Mann, Adam Aharon, Taeho Kim, Alexandre Ferrão Santos, Yi Zuo, Mark Hübener, Carla J. Shatz (2013) PirB regulates a structural substrate for cortical plasticity. Proceedings of the National Academy of Sciences
Xiaodong Tao, Oscar Azucena, Min Fu, Yi Zuo, Diana C. Chen, Joel Kubby (2012) Adaptive optics confocal microscopy using fluorescent protein guide-stars for brain tissue imaging. Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Min Fu, Xinzhu Yu, Ju Lu, Yi Zuo (2012) Repetitive motor learning induces coordinated formation of clustered dendritic spines in vivo. Nature
Xiaodong Tao, Bautista Fernández, Diana C. Chen, Oscar Azucena, Min Fu, Yi Zuo, Joel Kubby (2011) Adaptive optics confocal fluorescence microscopy with direct wavefront sensing for brain tissue imaging. Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Xiaodong Tao, Bautista Fernández, Oscar Azucena, Min Fu, Denise I. Garcia, Yi Zuo, Diana C. Chen, Joel Kubby (2011) Adaptive optics confocal microscopy using direct wavefront sensing. Optics Letters
Xiaodong Tao, Oscar Azucena, Min Fu, Yi Zuo, Diana C. Chen, Joel Kubby (2011) Adaptive optics microscopy with direct wavefront sensing using fluorescent protein guide stars. Optics Letters
Min Fu, Yi Zuo (2011) Experience-dependent structural plasticity in the cortex. Trends in Neurosciences
Monika S. Brill, Jeff W. Lichtman, Wesley J. Thompson, Yi Zuo, Thomas Misgeld (2011) Spatial constraints dictate glial territories at murine neuromuscular junctions. The Journal of Cell Biology
Xinzhu Yu, Yi Zuo (2010) Spine plasticity in the motor cortex. Current Opinion in Neurobiology
Tonghui Xu, Xinzhu Yu, Andrew J. Perlik, Willie F. Tobin, Jonathan A. Zweig, Kelly A. Tennant, Theresa A. Jones, Yi Zuo (2009) Rapid formation and selective stabilization of synapses for enduring motor memories. Nature
Yi Zuo, Derron L. Bishop (2008) Glial imaging during synapse remodeling at the neuromuscular junction. Neuron Glia Biology
Åsa Grunditz, Niklaus Holbro, Lei Tian, Yi Zuo, Thomas G. Oertner (2008) Spine Neck Plasticity Controls Postsynaptic Calcium Signals through Electrical Compartmentalization. Journal of Neuroscience
Hyuno Kang, Le Tian, Young‐Jin Son, Yi Zuo, Diane Procaccino, Flora M. Love, Christopher R. Hayworth, Joshua T. Trachtenberg, Michelle Mikesh, Lee Sutton, Olga Ponomareva, John Mignone, Grigori Enikolopov, Mendell Rimer, Wesley J. Thompson (2007) Regulation of the Intermediate Filament Protein Nestin at Rodent Neuromuscular Junctions by Innervation and Activity. Journal of Neuroscience
Dimitrios Davalos, Jaime Grutzendler, Guang Yang, Jiyun V. Kim, Yi Zuo, Steffen Jung, Dan R. Littman, Michael L. Dustin, Wen‐Biao Gan (2005) ATP mediates rapid microglial response to local brain injury in vivo. Nature Neuroscience
Yi Zuo, Aerie Lin, P Chang, Wen‐Biao Gan (2005) Development of Long-Term Dendritic Spine Stability in Diverse Regions of Cerebral Cortex. Neuron
Yi Zuo, Guang Yang, Elaine Kwon, Wen‐Biao Gan (2005) Long-term sensory deprivation prevents dendritic spine loss in primary somatosensory cortex. Nature
Yi Zuo, Jane L. Lubischer, Hyuno Kang, Le Tian, Michelle Mikesh, Alexander Marks, Virginia L. Scofield, Shan Maika, Craig S. Newman, Paul A. Krieg, Wesley J. Thompson (2004) Fluorescent Proteins Expressed in Mouse Transgenic Lines Mark Subsets of Glia, Neurons, Macrophages, and Dendritic Cells for Vital Examination. Journal of Neuroscience
Yi Zuo, Jay Z. Yeh, Toshio Narahashi (2004) Octanol Modulation of Neuronal Nicotinic Acetylcholine Receptor Single Channels. Alcoholism Clinical and Experimental Research
Yi Zuo, Keiichi Nagata, Jay Z. Yeh, Toshio Narahashi (2004) Single‐Channel Analyses of Ethanol Modulation of Neuronal Nicotinic Acetylcholine Receptors. Alcoholism Clinical and Experimental Research
Yi Zuo, Jay Z. Yeh, Toshio Narahashi (2003) Dual Action of n-Butanol on Neuronal Nicotinic α4β2 Acetylcholine Receptors. Journal of Pharmacology and Experimental Therapeutics
Yi Zuo, Alexander Kuryatov, Jon Lindstrom, Jay Z. Yeh, Toshio Narahashi (2002) Alcohol Modulation of Neuronal Nicotinic Acetylcholine Receptors Is ?? Subunit Dependent. Alcoholism Clinical and Experimental Research